A Microtubule-Myelination Connection
نویسندگان
چکیده
منابع مشابه
The Augmin Connection in the Geometry of Microtubule Networks
Microtubules mediate important cellular processes by forming highly ordered arrays. Organization of these networks is achieved by nucleating and anchoring microtubules at centrosomes and other structures collectively known as microtubule-organizing centers (MTOCs). However, the diverse microtubule configurations found in different cell types may not be generated and maintained by MTOCs alone. W...
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ome cells can induce the production of their own protective blanket. The signal comes from active neurons in the central nervous system (CNS), and triggers the differentiation of oligodendrocyte precursor cells (OPCs)—thus yielding the cells that cover the neurons with a protective sheath of myelin. Now, Beth Stevens, Douglas Fields, and colleagues (National Institutes of Health, Bethesda, MD) ...
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Myelin is a key evolutionary acquisition that underlay the development of the large, complex nervous systems of all hinged-jaw vertebrates. By promoting rapid, efficient nerve conduction, myelination also made possible the development of the large body size of these vertebrates. In addition to increasing the speed of nerve conduction, myelination has emerged as a source of plasticity in neural ...
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ژورنال
عنوان ژورنال: Cell
سال: 2019
ISSN: 0092-8674
DOI: 10.1016/j.cell.2019.08.046